Psoriasis | cigarettes psoriasis connection

Psoriasis | cigarettes psoriasis connection


Smoking… it’s bad for another reason…
next Study Further Establishes Smoking-Psoriasis
Connection Bill Schu writing in MD reported on a study
in the Polish population, published in Postępy, that clarifies and strengthens the link between
smoking and the development of psoriasis. Smoking releases large amounts of free radicals
that stimulate cell signaling pathways active in psoriasis. Nicotine present in cigarettes
also stimulates dendritic cells, macrophages and keratinocytes, releasing cytokines including
tumor necrosis factor (TNF), Interleukin-6, and others. Smoking can also increase the
expression of certain genes that can lead to psoriasis. Comment: The article also mentioned that depression
in people with psoriasis may lead them to habits such as smoking.

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